Showing posts with label journal of cell signaling mechanisms. Show all posts
Showing posts with label journal of cell signaling mechanisms. Show all posts

Monday, 29 May 2017

Single Nucleotide Polymorphism (SNP) and Its Preview

The announcement of human genome in June of 2000 pleasantly sent shock waves throughout the scholarly community and the general world population.
Nucleotide Polymorphism

It announced the completion of a draft of human genome, along with the arrival of post-genomic era. In fact, in the post-genomic era, we are focusing on DNA sequences, as these sequences in the human body determine the sphcific trait of an individual.

To fully understand the significanch of these sequences in the human body, we must first truly understand the "single nucleotide polymorphisms" (Single Nucleotide Polymorphism, SNP).

Tuesday, 9 May 2017

How Phospholipase C Regulates Stress Tolerance and Development in Plants?

How Phospholipase C Regulates Stress Tolerance and Development in Plants?

Phospholipase C
Lipid signaling pathways regulate many cellular processes in eukaryotes. PLCs are the major players in lipid signaling, triggered by numerous environmental cues in plants.

After hydrolysis, DAG remains attached to the membrane and activates protein kinase C (PKC) while IP3 moves to the cytoplasm to bind ligand gated Ca2+ channels (IP3 receptors) resulting in the release of Ca2+ from the intracellular reservoirs.

This model doesn’t hold completely true and still debatable in plant system, as the level of PI P2 in plant membrane is very low, and no IP3 receptors, and equivalents of animal PKC have not been identified till date in plants.