Monday, 17 April 2017

The Role of Vascular Endothelial Growth Factor Gene Polymorphisms in Recurrent Spontaneous Abortions in Saudi Women

Vascular endothelial growth factor (VEGF) genes regulate proliferation of vascular endothelial cells, hence, are essential for both physiological and pathological angiogenesis.

Polymorphisms in Recurrent Spontaneous Abortions in Saudi WomenThe aim of the present study was to examine the association between three common VEGF single nucleotide polymorphisms (-583 T/C, -1154 G/A, and 936 C/T) and the risk of RSA in Saudi women.

A total of 200 women; 100 with RSA-patient matched with 100 controls were enrolled sequentially. Genotyping was conducted using TaqMan assay in order to detect single nucleotide polymorphism (SNPs) in DNA extracts from blood samples.

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