The clinical and
immunological characteristics of 49 children with Down syndrome were studied.
Thirty-four boys and 15 girls between the ages of zero and six years old were
observed.
It was revealed
that children in the Study Group with Down syndrome developed a greater number
of disorders starting at the earliest stages of pregnancy and delivery, such as
fetal malnutrition, congenital heart defects, and pathology of vision, than
children in the control group (p<0.05).
All of the children in the
Study Group had allergic reactions and were
frequently ill. There was a noticed decrease in the numbers of subpopulations
of T-lymphocytes (СD45/CD3), CD3/CD4, CD3/CD8 and the absolute number of
B-cells (CD45/CD19), and at IgG pool, indicating a certain deficiency in
cell-mediated and humoral immune responses which provides a base for frequent
diseases, including bacterial diseases.
No comments:
Post a Comment