Atopic dermatitis (AD) is an
inflammatory skin disease with an onset in infancy or early childhood. It is
characterized by severe pruritus, chronic and relapsing course, and typical
clinical morphology including xerosis and eczematous lesions.
The incidence of AD has been
increasing during past 30 years, whereas its current prevalence is estimated
12%. Atopic
dermatitis is often associated with remarkable morbidity which results in
patient hospitalization, absence from work or school, and loss of several work
days.
In children, one of the most
hazardous effects of AD is sleep disorders which may lead to behavioral
disturbances. Furthermore, children are at risk of growth retardation as a
complication of the disease. Unpredictable course, chronic and relapsing nature
of the disease and disturbing pruritus can impose extensive psychological and
emotional burden to patients with AD and their families.
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