Monday, 8 May 2017

Airway Hyperresponsiveness in Asthma: A Better Understanding Yet to Yield Clinical Benefit

Seminal and ongoing research has made it clear that the molecular signature of asthma is not unique.
Seminal and ongoing research has made it clear that the molecular signature of asthma is not unique.  The molecular abnormalities that have been described in asthma are rather heterogeneous, and those that lead to asthma symptoms also differ between affected individuals.  This is not surprising, owing to the plethora of environmental factors that can trigger asthma. More than 500 individual triggers have been identified, including allergens, viruses, bacteria, pollutants, exercise, as well as occupational irritants and sensitizers. PDF LINK

The molecular abnormalities that have been described in asthma are rather heterogeneous, and those that lead to asthma symptoms also differ between affected individuals.

This is not surprising, owing to the plethora of environmental factors that can trigger asthma. More than 500 individual triggers have been identified, including allergens, viruses, bacteria, pollutants, exercise, as well as occupational irritants and sensitizers.

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