Considerable
studies have been done on the potential biological function of gelsolin and its
connection to human immune system, diseases and other disorders.
The objective of
our study was to identify genetic factors that regulate gelsolin in mouse
lung and analyze its function immune system using well
defined recombinant inbred strains.
For this purpose
we chose the BXD recombinant inbred (RI) strains derived from progeny of the
C57BL/6J (B6) and DBA/2J (D2) progenitor strains. Whole genome gene expression
in lung was used for the eQTL mapping.
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