Tuesday, 6 June 2017

Biomarkers of Bone Turnover: Potential, Challenges and Pitfalls from the Laboratory Point of view

Predominant Spine Involvement
The present review aim to describe the most commonly used serum bone formation and resorption biochemical markers, discuss their advantages and disadvantages and give practical information on their use and result interpretation in the laboratory and clinical settings according to current recommendations from International Scientific Societies.

Bone turnover markers (BTM) may give information on bone formation and resorption, risk of fracture and response to treatments.

BTMs have been extensively studied as markers in the diagnosis and monitoring of osteoporosis (OP), and resulted potentially useful as tools to evaluate the estimation of fracture future risk, although their significance was essentially demonstrated helpful to monitor efficacy of anti-OP treatments.

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